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7

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T26298 ts-SA

tsSA

ts-SA is a metalloenzyme carbonic anhydrase (CA) inhibitor. It is active against 7 out of 10 human CA isoforms.
T61032 Carbonic anhydrase inhibitor 10

Carbonic anhydrase inhibitor 10 可用于研究癌症,它对 MCF-7 癌细胞表现出抗增殖活性, IC50值为 11.9 μM。Carbonic anhydrase inhibitor 10 是 hCA IX 的有效抑制剂,Ki 值为 6.2 nM。
T28618 RS-93522

RS 93522

RS-93522 is an antagonist of calcium channel. RS-93522 had the additional property of inhibiting phosphodiesterase activity in myocardial homogenates (IC50 = 1.6 x 10(-5)M), the potency and efficacy of phosphodiesterase inhibition was similar to that for
T36059 Dichlorphenamide-13C6

Dichlorphenamide-13C6

Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively).1It lowers intraocular pressure in rabbits when 50 μl of a 10% solution is applied topically to the eye.2Dichlorphenamide rescues the potassium deficiency and prevents insulin-induc...
T72213 Efonidipine hydrochloride

NZ-105 hydrochloride

Efonidipine(NZ-105)盐酸盐是T 型和L 型钙离子通道双重阻断剂。
T41016 Vercirnon sodium

GSK-1605786 sodium,CCX282-Bsodium,维塞诺钠盐,Traficet-ENsodium

Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent antagonist of CCR9 . Vercirnon sodium inhibits CCR9-mediated Ca 2+ mobilization and chemotaxis on Molt-4 cells with IC 50 values of 5.4 and 3.4 nM, respectively. Vercirnon sodium is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC 50 s>10 μM for all). Vercirnon sodium is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC 50 values of 2.8 and 2.6 nM, respectivel...
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

化合物

ts-SA
Cat.No: T26298
Synonym: tsSA
Target:
Carbonic anhydrase inhibitor 10
Cat.No: T61032
Synonym:
Target:
RS-93522
Cat.No: T28618
Synonym: RS 93522
Target:
Dichlorphenamide-13C6
Cat.No: T36059
Synonym: Dichlorphenamide-13C6
Target:
Efonidipine hydrochloride
Cat.No: T72213
Synonym: NZ-105 hydrochloride
Target:
Vercirnon sodium
Cat.No: T41016
Synonym: GSK-1605786 sodium,CCX282-Bsodium,维塞诺钠盐,Traficet-ENsodium
Target:
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
Cat. No. Product Name Species Expression System
TMPY-01351 Carbonic Anhydrase 10 Protein, Human, Recombinant (His)

carbonic anhydrase X,CA-RPX,CARPX...

Human HEK293 Cells
Carbonic Anhydrase 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is A0A384MTY8.
TMPY-00693 Carbonic Anhydrase 10 Protein, Human, Recombinant

carbonic anhydrase X,CARPX,CA-RPX...

Human HEK293 Cells
Carbonic Anhydrase 10 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.2 kDa and the accession number is A0A384MTY8.
TMPY-01751 DR3/TNFRSF25 Protein, Human, Recombinant (hFc)

TRAMP,TR3,WSL-1,TNFRSF12,DR3,WSL-LR,tumor necrosis factor re...

Human HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-05760 DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated

TRAMP,tumor necrosis factor receptor superfamily, member 25,...

Human HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961 ADAM15 Protein, Human, Recombinant (His)

MDC15,ADAM metallopeptidase domain 15

Human HEK293 Cells
ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.
TMPY-02300 BIN1 Protein, Human, Recombinant (His)

AMPHL,bridging integrator 1,AMPH2,SH3P9

Human E. coli
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicated in rare and common diseases affecting different tissues and physiological functions. BIN1 downregulation is linked to cancer progression and also correlates with ventricular cardiomyopathy and arrhythmia preceding heart failure. Increased BIN1 expression is linked to increased...

重组蛋白

Carbonic Anhydrase 10 Protein, Human, Recombinant (His)
Cat.No: TMPY-01351
Species: Human
Expression System: HEK293 Cells
Carbonic Anhydrase 10 Protein, Human, Recombinant
Cat.No: TMPY-00693
Species: Human
Expression System: HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01751
Species: Human
Expression System: HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05760
Species: Human
Expression System: HEK293 Cells
ADAM15 Protein, Human, Recombinant (His)
Cat.No: TMPY-00961
Species: Human
Expression System: HEK293 Cells
BIN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02300
Species: Human
Expression System: E. coli
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